• Samuel - "Sometimes I wonder about you, Sam."
• Sam - "Sometimes I wonder about me too."

• Lisa - "Dean, no offense, but if you don't walk out that door, I'm going to shoot you."

• Sam - "Seat belt."
• Dean - "What am I, in third grade?"

• Dean - "There's a little bit too much mystery in this family for me to get comfy."
  

More Two and a Half Men Quotes

• Who was on the other end of the phone with Samuel?
  
• Dean voiced some suspicions to Sam -- what does he think is happening?
  

• Samuel seems to be working for someone, apparently collecting "monsters."
  
• Dean is torn between two worlds.
  
• The Impala finally comes out from under the tarp!
  

• Sam's license plate is I4Z 0892

• The pattern in this episode involves six-month-old babies, just as when YED was creating his army.
  

More Two and a Half Men Trivia

• The title refers to the series Two and a Half Men, starring Jon Cryer, Charlie Sheen as his womanizing brother, and Angus T. Jones as his son.
  
• Sam tells Dean, "Welcome to the party, Gutenberg," an allusion to Steve Gutenberg in the movie Three Men and a Baby.
  
• When Dean is able to calm down the baby, Sam tells him he's got a "whole Dr. Huxtable vibe," an allusion to Bill Cosby's role on The Cosby Show.
  

More Two and a Half Men Allusions

• Deep Purple - "Smoke on the Water"

• Daniel May/Master Source -"Shop 'Til You Drop"

Strange things similar to plagues begin happening, and San and Dean try to contact Castiel, only to find out that he needs their help as well.

EPISODE 603: THE THIRD MAN