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As the scene opens, we see Donatello at home baking cookies and cooking. Suddenly, someone rings the doorbell urgently. When Donatello opens the door, he’s attacked by someone whose face we can’t see.
Next, we see Donatello tied down to a table. The stranger pulls out a large syringe and injects something into Donatello’s neck as the prophet screams.
At the bunker, Dean, Sam, Mary and Jack have apparently decided to have a “game night” to help everyone relax. While Mary and Jack prepare popcorn and other snacks, Dean attempts to play a game (Mouse Trap) that used to be his favorite (according to Mary) when he was a child. Dean can’t get the game to work properly and quickly gets frustrated.
CASTIEL and ANAEL
At a diner in an undisclosed location, Castiel and Anael meet to talk. Apparently, Castiel has called the meeting because he wants Anael’s help contacting Chuck. Cas offers Anael a pair of rare, antique earrings if she’ll agree to help him. Cas seems to believe that Jack has lost his soul (or most of it) and Chuck is the only one who can restore it. Cas goes on to say that he knows Anael was friends with Joshua, who used to talk to Chuck, so he believes she can help Cas do the same thing. Cas also confesses that the Winchesters don’t know he asked for their meeting or what he’s planning.
Anael initially refuses to help, accusing Cas of being desperate and telling him that Chuck spoke to Joshua and not the other way around. However, when she realizes that she won’t get the earrings, she confesses that she’s hears rumors about a call Joshua placed to Chuck after the angels fell, and Chuck answered. Anael says she doesn’t know how the call was made, but she agrees to take Cas to someone who was there.
Later that night, Castiel and Anael arrive at an antique store/junk store run by an angel named Methuselah. It seems that Methuselah and Joshua were friends and Methuselah sheltered Joshua after the fall. Castiel demands to know how Joshua contacted Chuck. After a brief conversation, Methuselah tells Cas and Anael that the object Joshua used to contact Chuck is in the store someplace, but he doesn’t know what it looks like or exactly where it is. He says they’ll know it when they find it.
Next, we see Castiel and Anael leaving the store. Before they part ways, Cas tells Anael that he’s going to tell Dean and Sam the truth. He also tries to tell her that they (angels and humans) are not alone, because they have each other. She dismisses him.
DEAN and SAM
Later, Dean and Sam talk via cell phone. Dean thinks Donatello was perhaps possessed and speaking in tongues, but Sam thinks he recognizes the language as ancient Hebrew and agrees to try to translate what Donatello was saying.
After Dean hangs up, he and Mary talk briefly. Mary comments that everyone seems very stressed and she wishes there was something she could do. Dean reminds Mary that her being with them is helpful and means a lot to all of them. Mary says she wishes she could’ve been there more, and that she’s grateful for every day she gets to spend with him and Sam.
At the bunker, Sam translates Donatello’s message. It’s apparently a verse from the bible that warns “Be sober. Be vigilant, because your adversary, the devil , as a roaring lion, walks abut seeking whom he may devour.”
Elsewhere, Dean and Mary arrive at Donatello’s house and rush inside. Donatello isn’t there, but Nick is. Dean handcuffs Nick and orders him to tell them where Donatello is. Nick refuses, and as Mary searches the house, Nick and Dean talk. Nick reveals that he escaped from the police and killed some people. When Mary returns, we see that she has found the syringe Nick used to inject Donatello. After further questioning and threats, Nick shows Dean and Mary a cell phone running a live video feed of Donatello tied up someplace, calling for help. He also tells them that he has poisoned Donatello with thallium, and the prophet will die unless they agree to talk to him. At first, Dean threatens to kill Nick, but after quick consideration, they agree to Nick’s demand.
Dean and Mary arrive at the bunker with Nick. Sam is furious, but agrees to try to hack the live video feed to see where it’s coming from. He also tells Dean that they have Prussian blue – the antidote for thallium toxicity -- and if they find Donatello in time they can save him. Later, Sam and Mary are talking alone and Sam admits that he blames himself for what Nick did because he’s the one who let him go. Mary insists that Sam did what he did because he’s a good man, and he shouldn’t blame himself.
In the bunker’s dungeon, Dean tries unsuccessfully to beat the truth out of Nick. Nick berates Dean and refuses to answer, but insists that he wants to talk to Jack. Initially, Mary, and Dean refuse to allow Nick to talk to Jack, but after a group discussion, everyone (including Jack) agrees.
Later, Jack rejoins the others and announces that Nick has agreed to take them to Donatello.
Some time later, we see Dean and Sam driving Nick to a deserted warehouse. It’s daylight, so they’ve been driving all night. Dean enters the warehouse with the antidote, while Sam waits in the car with Nick.
MARY and JACK
Back at the bunker, Mary and Jack look over the items they found at Donatello’s house. When Jack notices the syringe, he picks it up and say she can sense angel grace. He tells Mary that the syringe must have contained angel grace. Mary surmises that Nick must have somehow injected Donatello with angel grace, so the whole thing about thallium was a lie. She calls Sam to warn him…
DEAN and SAM
Dean enters the warehouse and frees Donatello…
Meanwhile, outside in the car, Sam gets Mary’s call. While Sam is outside the car talking, Nick frees himself from the handcuffs. Once Sam realizes they’ve been tricked, he forces Nick out of the car at gun point and orders him to reveal what he’s doing.
Nick tells Sam that prophets can be used like radios, and that angel grace can boost the signal. He goes on to say that Lucifer is awake in the Empty, and that – by using Donatello as a radio – Lucifer was able to tell Nick how to resurrect him. Nick adds that he got the angel grace from demons, who want Lucifer back as badly as he does. He also reveals that he needed Jack’s blood for the resurrection spell, which his why he needed to get to Jack. Suddenly, Nick drops the handcuffs on the ground and attacks Sam. Sam calls for Dean…
Inside the warehouse, Dean hears Sam call. But suddenly he’s attacked by two demons…
Sam and Nick fight, and Sam temporarily overpowers Nick. He begins choking Nick, but stops before he kills him. Nick picks up a rock and hits Sam in the head, then renews his attack. Sam is badly injured, but is able to lock himself inside the car away from Nick. As Nick escapes, Sam urgently honks the horn, alerting Dean that he’s in trouble.
Inside the warehouse, Dean kills both demons. Suddenly, he hears the car horn and he and Donatello rush outside to help Sam.
When Dean arrives at the car, he finds Sam gravely injured and lying on the ground, bleeding badly from the head. Nick is gone…
Dean holds a bandana to Sam’s head to slow down the bleeding, and calls Mary. He tells Mary that Nick tricked them and is trying to resurrect Lucifer. He also says that Sam is too badly injured to be moved and the ambulance will take 20 minutes to arrive. The expression on Dean's face and the tone of his voice suggest that he doesn't think Sam will survive.
Elsewhere, we see Nick car jack a passerby and use his car to go to a remote cabin. Nick hastily assembles some ingredients – including his shirt with Jack’s blood on it -- and begins performing the spell to bring Lucifer back from the Empty.
Back at the bunker, when Nick begins performing the spell, Jack doubles over in pain, saying that it feels like his blood is on fire. Mary realizes that Nick is performing the spell as they speak, and that getting Jack’s blood was the reason for Nick’s elaborate scheme to get into the bunker and get time alone with Jack. She tells Jack that they have to stop Nick, and insists that Jack use his powers to teleport to Nick’s location so they can stop him.
Mary and Jack arrive at the cabin just in time to stop Nick. As Lucifer steps from the Empty and reaches for Nick, Jack uses his powers to force Lucifer back (it seems) into the Empty. Jack then uses his powers to torture Nick and slowly incinerate him. Mary realizes that Jack is killing Nick and tries to get him to stop, but by the time he does, Nick is badly burned and unconscious on the floor – possibly dead. Mary seems horrified by what Jack has done, but asks Jack to go help Sam. Jack teleports away.
Next, we see Dean kneeling next to Sam, who slips into unconsciousness (or death). Jack suddenly appears and heals Sam, much to Dean’s relief. Jack also tells the brothers that he stopped Nick, Mary is fine, and everything is okay now. He then leaves to re-join Mary at the cabin.
Back at the cabin, Jack tells Mary that he healed Sam, so things are okay. Mary seems afraid of Jack because of what he did to Nick, but Jack insists that Nick was a bad person and deserved to be punished and had to be stopped. Mary agrees, but says that Jack went too far. Jack wants Mary to say that things are okay, but Mary tries to tell him that something is wrong with him. Jack asks Mary not to tell Dean and Sam what he did. When Mary persists, saying that they’ll help him and work things out, Jack tries to walk away from her. Suddenly, Jack starts holding his head like he’s in pain, and we hear a loud ringing sound that Mary doesn’t seem to hear. Jack starts shouting “leave me alone” and continues holding his head and trying to evade Mary, who follows behind him trying to talk to him.
Suddenly, Jack’s eyes glow yellow and he shouts “Leave me alone!” one last time. Mary is off screen, but she doesn’t reply and Jack whispers her name as if something has happened to her.